stadio: Alerus Center Round: 1
Home Manager: Bubba Schweigert Away Manager: Doug Phillips
| NCAAF | 2021/10/30 18:00 | South Dakota State v Youngstown State | L | 47-16 |
| NCAAF | 2021/10/23 17:00 | Youngstown State v Indiana State | L | 17-28 |
| NCAAF | 2021/10/09 18:00 | Missouri St v Youngstown State | W | 33-41 |
| NCAAF | 2021/10/02 21:00 | Youngstown State v Northern Iowa | L | 7-34 |
| NCAAF | 2021/09/25 22:00 | Western Illinois v Youngstown State | L | 38-35 |
| NCAAF | 2021/09/11 16:00 | Youngstown State v Michigan State | L | 14-42 |
| NCAAF | 2021/09/02 23:00 | Incarnate Word v Youngstown State | W | 41-44 |
| NCAAF | 2021/04/10 19:00 | Youngstown State v Missouri St | L | 10-21 |
| NCAAF | 2021/10/30 19:00 | North Dakota v Missouri St | L | 28-32 |
| NCAAF | 2021/10/23 19:00 | Western Illinois v North Dakota | W | 10-34 |
| NCAAF | 2021/10/16 19:00 | North Dakota v SO Illinois | L | 28-31 |
| NCAAF | 2021/10/09 19:00 | North Dakota v South Dakota | L | 13-20 |
| NCAAF | 2021/10/02 19:00 | North Dakota State v North Dakota | L | 16-10 |
| NCAAF | 2021/09/18 21:00 | Drake Bulldogs v North Dakota | W | 0-38 |
| NCAAF | 2021/09/11 01:00 | North Dakota v Utah State | L | 24-48 |
| NCAAF | 2021/09/04 19:00 | North Dakota v Idaho State | W | 35-14 |