Head to Head
| NFL | 2018/12/23 21:05 | CHI Bears v SF 49ers | L | 14-9 |
| NFL | 2017/12/03 18:00 | SF 49ers v CHI Bears | W | 15-14 |
| NFL | 2016/12/04 18:00 | SF 49ers v CHI Bears | L | 6-26 |
| NFL | 2015/12/06 18:00 | CHI Bears v SF 49ers | W | 20-26 |
| NFL | 2014/09/15 00:30 | SF 49ers v CHI Bears | L | 20-28 |
Home History
| NFL | 2021/10/25 00:20 | IND Colts v SF 49ers | L | 30-18 |
| NFL | 2021/10/10 20:25 | SF 49ers v ARZ Cardinals | L | 10-17 |
| NFL | 2021/10/03 20:05 | SEA Seahawks v SF 49ers | L | 28-21 |
| NFL | 2021/09/27 00:20 | GB Packers v SF 49ers | L | 30-28 |
| NFL | 2021/09/19 17:00 | SF 49ers v PHI Eagles | W | 17-11 |
| NFL | 2021/09/12 17:00 | SF 49ers v DET Lions | W | 41-33 |
| Preseason NFL | 2021/08/29 20:00 | LV Raiders v SF 49ers | W | 10-34 |
| Preseason NFL | 2021/08/22 23:30 | SF 49ers v LA Chargers | W | 15-10 |
Away History
| NFL | 2021/10/24 20:25 | CHI Bears v TB Buccaneers | L | 3-38 |
| NFL | 2021/10/17 17:00 | GB Packers v CHI Bears | L | 24-14 |
| NFL | 2021/10/10 20:05 | CHI Bears v LV Raiders | W | 20-9 |
| NFL | 2021/10/03 17:00 | DET Lions v CHI Bears | W | 14-24 |
| NFL | 2021/09/26 17:00 | CHI Bears v CLE Browns | L | 6-26 |
| NFL | 2021/09/19 17:00 | CIN Bengals v CHI Bears | W | 17-20 |
| NFL | 2021/09/13 00:20 | CHI Bears v LA Rams | L | 14-34 |
| Preseason NFL | 2021/08/28 23:00 | CHI Bears v TEN Titans | W | 27-24 |
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