stadio: John O'Quinn Field at TDECU Stadium Round: 1
Home Manager: Major Applewhite Away Manager: Michael Haywood
| NCAAF | 2018/09/15 23:00 | Texas Southern Tigers v Alcorn State | L | 15-27 |
| NCAAF | 2018/09/08 23:00 | Texas Southern Tigers v Texas State | L | 20-36 |
| NCAAF | 2018/09/02 00:00 | Texas Southern Tigers v Texas-Permian Basin Falcons | W | 26-16 |
| NCAAF | 2017/11/26 00:00 | Texas Southern Tigers v Prairie View | L | 16-30 |
| NCAAF | 2017/11/18 20:30 | Arkansas Pine Bluff v Texas Southern Tigers | W | 10-24 |
| NCAAF | 2017/11/11 23:00 | Texas Southern Tigers v Southern | L | 7-33 |
| NCAAF | 2017/11/04 18:00 | Mississippi Valley State v Texas Southern Tigers | W | 21-38 |
| NCAAF | 2017/10/28 19:00 | Grambling State v Texas Southern Tigers | L | 50-24 |
| NCAAF | 2018/09/15 20:15 | Houston v Texas Tech | L | 49-63 |
| NCAAF | 2018/09/08 16:00 | Arizona v Houston | W | 18-45 |
| NCAAF | 2018/09/01 16:00 | Houston v Rice | W | 45-27 |
| NCAAF | 2017/12/25 01:30 | Houston v Fresno State | L | 27-33 |
| NCAAF | 2017/11/24 17:00 | Navy v Houston | W | 14-24 |
| NCAAF | 2017/11/18 21:00 | Houston v Tulane | L | 17-20 |
| NCAAF | 2017/11/04 16:00 | East Carolina v Houston | W | 27-52 |
| NCAAF | 2017/10/28 19:45 | Houston v South Florida | W | 28-24 |